Prostate health is a central concern for men considering testosterone therapy — and for all men over 40. PSA (prostate-specific antigen) testing is the primary screening tool for prostate cancer and a mandatory monitoring marker for men on testosterone therapy. Understanding what PSA measures, how to interpret it, and what TRT's actual relationship to prostate health is will help you navigate this topic with confidence. What PSA Measures PSA is a protein produced by both norm